Trixi is a diminutive of the German name trilogy, which means "third". It has been used as an independent given name since the late 19th century in Germany and Austria-Hungary. The name gained popularity during the interwar period in Central Europe, particularly among Jewish communities in Vienna. Today, Trixi is still more commonly used in German-speaking countries than elsewhere.
In the United States, the name Trixi experienced a brief period of popularity with five babies being given this name in both 1976 and 1994. This brings the total number of children born with the name Trixi in the U.S. to ten over these two years combined.