Calise is an Italian given name derived from the Latin word "calix," meaning "cup" or "chalice." It holds historical significance as it was often given to boys in medieval Italy to honor the sacred chalice used during communion services, symbolizing the blood of Christ. Saint Calise, a 4th-century Christian martyr, is associated with this name. Despite its rarity today, Calise remains an uncommon yet captivating choice for parents seeking a distinctive and meaningful name with rich historical roots.