Kathyrine is a Greek-origin feminine given name meaning "pure" or "clear," popularized during the Middle Ages due to Saint Catherine of Alexandria's veneration. It has been borne by notable figures like Catherine de' Medici and Catherine the Great, and used in literature by authors such as Emily Brontë. Today, Kathyrine remains a popular choice for girls with variants including Kathy, Katie, Kat, and Kathryn.